The VALIDATE Network - Vaccine development for complex intracellular neglected pathogens
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Pathogens

VALIDATE focuses on three pathogens groups that cause diseases that have significant impact on low and middle-income countries: Mycobacterium (causing TB, leprosy and other diseases), leishmanias (leishmaniasis), and Burkholderia pseudomallei (melioidosis).

Click below to find out more about these diseases and our research on the pathogens that cause them:

mycobacterium tuberculosis

Tuberculosis

Tuberculosisis is a global disease caused by a bacterium, Mycobacterium tuberculosis. In 2020 10 million people developed TB and 1.5 million died, killing more people every year than HIV or malaria.
leishmania

Leishmaniasis

Leishmaniasis refers to a diverse group of diseases caused by single-celled parasites called Leishmania. About 12 million people are infected at any one time, causing up to 30,000 deaths annually.
burkholderia pseudomallei

Melioidosis

Melioidosis is a disease caused by a bacterium, Burkholderia pseudomallei, and is found across tropical and semi-tropical regions worldwide. An estimated 165,000 people develop melioidosis annually with 89,000 of these cases being fatal.
mycobacterium leprae

Leprosy

Leprosy is a chronic neglected disease caused by the bacterium Mycobacterium leprae. There are an estimated 120,000 new cases of leprosy are diagnosed every year.
Mycobacterium tuberculosis

Buruli ulcer

Buruli ulcer is a chronic neglected tropical disease caused by Mycobacterium ulcerans, primarily affecting the skin and soft tissue in tropical and subtropical regions with limited healthcare access.